Institute of Cell Biology

Research in Cell Biology is directed towards an understanding of the molecular mechanisms that underpin genomic and cellular structure and function.

Computer-generated image of a cell.

Situated in the Rutherford-Swann-Waddington complex as well as the Roger Land Building at King’s Buildings, provides a state-of-the-art environment for cell and molecular biology.

A number of research centres are incorporated. The Centre for Chemical and Translational Biology provides world class facilities for protein production and biophysical characterisation. The Centre for Synthetic and Systems Biology (SynthSys) is a unique interdisciplinary environment and is currently developing genetic and molecular tools for re-designing biochemical systems.

The funders of research being carried out within the these research areas include BBSRCCR-UK, European Commission, Gates Foundation, Mayo Foundation, MRC, Royal Society and Wellcome Trust.

We tackle major biological questions working with a wide range of experimental systems including cell culture, bacteria, yeast, Drosophila and mouse.

We also carry out studies of the processes underlying microbial physiology and pathogenesis.

We work closely with members of Quantitative Biology, Biochemistry and Biotechnology with whom we have common research interests and collaborative projects.

Our research falls into nine topics as indicated below:

  • Cell structure and development
  • Chromosome structure and the cell cycle
  • DNA repair and genome stability
  • Drug Discovery
  • Epigenetic control of gene expression
  • Macromolecular structure and interaction
  • Microbial physiology and pathogenesis
  • RNA Biology
  • Systems and Synthetic Biology